Dr. Nofar Mintz Hemed
23/01/2025
אודיטוריום ע"ש דויד וואנג, בניין מידן, קומה 3
14:30
Continuous, real-time insights into clinically relevant biomarkers can transform healthcare by enabling early detection of deviations from normal bodily functions, facilitating timely interventions and personalized treatment plans. Advances in materials engineering and biosensor technology have enhanced in-vivo physiological monitoring, but challenges in stability, sensitivity, and reversibility must be addressed.
In this seminar, I will discuss the requirements and approaches for reliable monitoring of complex physiological signals, focusing on sensor design and performance. I will present electrochemical biosensors based on molecularly imprinted polymer (MIP) technology, highlighting solutions to the sensitivity-reversibility tradeoff. This advancement includes an ultra-sensitive MIP-based melatonin microwire sensor for tracking circadian rhythms and mitigating jet lag in warfighters, as well as a scalable microwire array for precise, real-time dopamine monitoring.
My future research will encompass all aspects of biosensor advancement, from innovative design to insertion and encapsulation. I aim to develop sensors leveraging trends in miniaturization and personalization while exploring advanced encapsulation strategies. Additionally, improving biosensor insertion into tissues while balancing strength, design, and minimized tissue damage is a priority. This comprehensive approach will enhance device functionality and interaction, promoting better patient outcomes and advancing healthcare diagnostics and treatment.