(A) Manuscripts in Peer-Reviewed Journals 

    1. Moglioni AG, Martínez AR, Sosnik A, Moltrasio Iglesias GY, Synthesis and study of reactivity in the Diels-Alder reaction of 3-carbometoxi-2(5H)-indano [1,2-b] pyranones, J Chem Res Synop 11, 500-501 (1996).
    2. Cohn D, Sosnik A, Novel reverse thermo-responsive injectable poly(ether carbonate)s, J Mat Sci Mater Med 14, 175-180 (2003).
    3. Sosnik A§, Cohn D, San Román J, Abraham GA, Crosslinkable PEO-PPO-PEO-based reverse thermo-responsive gels as potentially injectable materials, J Biomater Sci Pol Edn 14, 227-239 (2003).
    4. Cohn D, Sosnik A, Levy A, Improved reverse thermo-responsive polymeric systems, Biomaterials 24, 3707-3714 (2003).
    5. Sosnik A§, Cohn D, Poly(ethylene glycol)-poly(epsilon-caprolactone) block oligomers as injectable materials, Polymer 44, 7033-7042 (2003).
    6. Sosnik A, Cohn D, Ethoxysilane-capped PEO-PPO-PEO triblocks: A new family of reverse thermo-responsive polymers, Biomaterials 25, 2851-2858 (2004).
    7. Sosnik A, Cohn D., Reverse thermo-responsive poly(ethylene oxide) and poly(propylene oxide) multiblock copolymers, Biomaterials 26, 349-357 (2005).
    8. Cohn D, Sosnik A, Garty S, Smart hydrogels for in situ-generated implants, Biomacromolecules 6, 1168-1175 (2005).
    9. Sosnik A, Sefton MV, Semi-synthetic collagen/poloxamine matrices for Tissue Engineering, Biomaterials 26, 7425-7435 (2005).
    10. Sosnik A, Leung B, McGuigan AP, Sefton MV, Collagen/poloxamine hydrogels: Cytocompatibility of embedded HepG2 cells and surface attached endothelial cells, Tissue Eng A 11, 1807-16 (2005).
    11. Sosnik A, Sefton MV, Poloxamine hydrogels with a quaternary ammonium modification to improve cell attachment, J Biomed Mater Res-A 75, 295-307 (2005).
    12. Sosnik A§, Brodersen P, Sodhi RNS, Sefton MV, Surface study of collagen/poloxamine hydrogels by a ‘deep freezing’ ToF-SIMS approach, Biomaterials 27, 2340-2348 (2006).
    13. Sosnik A, Sefton MV, Methylation of poloxamine for enhanced cell adhesion, Biomacromolecules 7, 331-338 (2006).
    14. Cohn D, Lando G, Sosnik A, Garty S, Levi A, PEO–PPO–PEO-based poly(ether ester urethane)s as degradable reverse thermo-responsive multiblock copolymers, Biomaterials 27, 1718-1727 (2006).
    15. Sosnik A§, Injectable biomaterials for biomedical and pharmaceutical applications: Past, present and future of the in situ generated implants, ARS Pharm 48, 83-102 (2007).
    16. Chiappetta DA, Sosnik A§, Poly(ethylene oxide)-Poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs,Eur J Pharm Biopharm 66, 303-317 (2007).
    17. Sosnik A, Leung BM, Sefton MV, Lactoyl-poloxamine/collagen matrix for cell-containing modules, J Biomed Mater Res-A 86, 339-53 (2008).
    18. Cohn D, Sosnik A, Malal R, Zarka R, Garty S, Levy A, Chain extension as a strategy for the development of improved reverse thermo-responsive polymers, Polym Adv Tech 18, 731-736 (2007).
    19. Chiappetta DA, Degrossi J, Teves S, D´Aquino M, Bregni C, Sosnik A§, Triclosan-loaded poloxamine micelles for enhanced antibacterial activity against biofilm, Eur J Pharm Biopharm 69, 535-545 (2008).
    20. Sosnik A§, Carcaboso A, Chiappetta DA, Polymeric nanocarriers: New endeavors for the optimization of the technological aspects of drugs, Recent Pat Biomed Eng 1, 43-59 (2008).
    21. Carcaboso A, Chiappetta DA, Höcht C, Blake MM, Boccia MM, Baratti CM, Sosnik A§, Melt-molding/compression manufacturing and in vitro-in vivo characterization of gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies, Eur J Pharm Biopharm 70, 666-673 (2008).
    22. Pacheco DO, Aragón DM, Ruizdíaz MA, Sosnik A, Martínez F, Extended Hildebrand solubility approach in the estimation of naproxen solubility in ethanol/water co-solvent mixtures, Vitae 15, 113-122 (2008).
    23. Gonzalez-Lopez J, Alvarez-Lorenzo C, Taboada P, Sosnik A, Sandez-Macho I, Concheiro A, Self-associative behavior and drug solubilizing ability of poloxamine (Tetronic) block copolymers, Langmuir 24, 10688–10697 (2008).
    24. Aragón DM, Chiappetta DA, Degrossi J, Vargas EF, Bregni C, Sosnik A, Martínez F, Gibbs energy of transfer processes for the antimicrobial agent Triclosan from water to some organic solvents at 25.0°C, Rev Colomb Cienc Quim Farm 37, 237-251 (2008).
    25. Aragón DM, Chiappetta DA, Vargas EF, Sosnik A, Martínez F, Gibbs energy of transfer for the antimicrobial agent triclosan from water to some organic solvents at 298.15 K, J Chem Eng Data 53, 2576-2580 (2008).
    26. Vargas EF, Sosnik A, Rodríguez F, Application of the Jouyban-Acree model for the estimation of the solubility of naproxen in ethanol/water co-solvent mixtures, Lat Am J Pharm 27, 654-660 (2008).
    27. Torres DR, Sosnik A, Chiappetta DA, Vargas EF, Rodríguez Martínez F, Dissolution enthalpy of sodium sulfacetamide in water: Comparison between solution isoperibolic calorimetry and the Van´t Hoff method, Quim Nova 31, 1455-1459 (2008).
    28. Aragon DM, Sosnik A, Martínez F, Solution thermodynamics of triclocarban in organic solvents of different hydrogen bonding capability, J Sol Chem 38, 1493-1503 (2009).
    29. Sosnik A§, Chiappetta DA, Carcaboso A, Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead, J Control Release 138, 2-15 (2009).
    30. Chiappetta DA, Carcaboso AM, Bregni C, Rubio MC, Bramuglia G, Sosnik A§, Indinavir-loaded ph-sensitive microparticles for taste masking: towards extemporaneous paediatric HIV/AIDS liquid formulations with improved patient compliance, AAPS PharmSciTech 10, 1-6 (2009).
    31. Alvarez-Lorenzo C, Rey-Rico A, Brea J, Loza MI, Concheiro A, Sosnik A§, Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: Branched versus linear derivatives, Nanomedicine (Lond.) 5, 1371-1383 (2010).
    32. Sosnik A§, Nanotechnology contributions to the pharmacotherapy of pediatric HIV: A dual scientific and ethical challenge and a still pending agenda, Nanomedicine (Lond.) 5, 833-837 (2010).
    33. Chiappetta DA, Alvarez-Lorenzo C, Rey-Rico A, Taboada P, Concheiro A, Sosnik A§, N-alkylation of poloxamines modulates micellar encapsulation and release of the antiretroviral efavirenz, Eur J Pharm Biopharm 76, 24-37 (2010).
    34. Moretton MA, Glisoni RJ, Chiappetta DA, Sosnik A§, Molecular implications in the nanoencapsulation of the antituberculosis drug rifampicin within flower-like polymeric micelles, Colloids Surf B: Biointerfaces 79, 467-479 (2010).
    35. Glisoni RJ, Chiappetta DA, Finkielsztein LM, Moglioni AG, Sosnik A§, Self-aggregation behaviour of novel thiosemicarbazone drug candidates with potential antiviral activity, New J Chem 34, 2047-2058 (2010).
    36. Cuestas ML, Mathet V, Oubiña JR, Sosnik A§, Drug delivery systems and liver-targeting for the improved pharmacotherapy of the Hepatitis B virus (HBV) infection, Pharm Res 27, 1184-1202 (2010).
    37. Chiappetta DA, Hocht C, Sosnik A§, A highly concentrated and taste-improved aqueous formulation of efavirenz for a more appropriate paediatric management of the anti-HIV therapy, Curr HIV Res 8, 23-31 (2010).
    38. Blake MG, Mariano Boccia M, Carcaboso AM, Chiappetta D, Höcht C, Krawczyk M, Sosnik A, Baratti CM, Novel long-term anticonvulsive treatment with gabapentin without causing memory impairment in mice, Epilepsy & Behavior 17, 157-164 (2010).
    39. Espinosa L, Sosnik A, Fontanilla MR, Development and pre-clinical evaluation of acellular collagen scaffolding and autologous artificial connective tissue in the regeneration of oral mucosa wounds, Tissue Eng A 16, 1667-1679 (2010).
    40. Chiappetta DA, Hocht C, Taira C, Sosnik A§, Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailaibility, Nanomedicine (Lond.) 5, 11-23 (2010).
    41. Kurkalli BGS, Gurevitch O, Sosnik A, Cohn D, Slavin S, Repair of bone defect using bone marrow cells and demineralized bone matrix supplemented with polymeric materials, Curr Stem Cell Res Ther 5, 49-56 (2010).
    42. Sosnik A§, Amiji M, Nanotechnology solutions for infectious diseases in developing nations, Adv Drug Deliv Rev 62, 375-377 (2010).
    43. Sosnik A§, Chiappetta DA, Moretton MA, Glisoni RJ, Carcaboso A, New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery, Adv Drug Deliv Rev 62, 547-559 (2010).
    44. Alvarez-Lorenzo C, Rey-Rico A, Sosnik A, Taboada P, Concheiro A, Poloxamine-based nanomaterials for drug delivery, Frontiers Biosci E2, 424-440 (2010).
    45. Carcaboso A, Chiappetta DA, Opezzo AW, Höcht C, Fandiño AC, Croxatto JO, Rubio MC, Sosnik A, Bramuglia GF, Abramson DH, Chantada GL, Episcleral implants for topotecan delivery to the posterior segment of the eye, Invest Ophthamol Vis Sci 51, 2126-2134(2010).
    46. Andrade F, Goycoolea F, Chiappetta DA, das Neves J, Sosnik A, Sarmento B, Chitosan-grafted copolymers and chitosan-ligand conjugates as matrices for pulmonary drug delivery, Int J Carbohyd Chem 2011, Art. ID 865704 (2011).
    47. Peroni RN, Di Gennaro SS, Hocht C, Chiappetta DA, Rubio MC, Sosnik A, Bramuglia GF, Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat, Biochem Pharmacol 82, 1227-1233 (2011).
    48. Cuestas ML, Sosnik A, Mathet VL, Poloxamines display a multiple inhibitory activity of ATP-Binding Cassette (ABC) transporters in cancer cell lines, Mol Pharmaceutics 8, 1152-1164 (2011).
    49. Chiappetta DA, Facorro G, Rubin de Celis E, Sosnik A§, Synergistic encapsulation of the anti-HIV agent efavirenz within poly(ethylene oxide)-poly(propylene oxide) mixed polymeric micelles, Nanomedicine: Nanotechnol Biol Med 7, 624-637 (2011).
    50. Chiappetta DA, Hocht C, Taira C, Sosnik A§, Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles, Biomaterials 32, 2379-2387 (2011).
    51. Sosnik A§, Gotelli G, Abraham GA, Microwave-assisted polymer synthesis (MAPS) as a tool in biomaterials science: How new and how powerful, Prog Polym Sci 36, 1050-1078 (2011).
    52. Gotelli G, Bonelli P, Abraham G, Sosnik A§, Fast and efficient synthesis of high molecular weight poly(epsilon-caprolactone) diols by Microwave-Assisted Polymer Synthesis (MAPS), J Appl Polym Sci 121, 1321-1329 (2011).
    53. Alvarez-Lorenzo C, Sosnik A, Concheiro A, PEO-PPO block copolymers for passive micellar targeting and overcoming multidrug resistance in cancer therapy, Curr Drug Targets 12, 1112-1130 (2011).
    54. Delgado DR, Sosnik A, Martínez F, Transfer thermodynamics of triclosan from water to organic solvents with different hydrogen bonding capability, Lat Am J Pharm 30, 459-466 (2011).
    55. Cuestas ML, Castillo A, Sosnik A, Mathet VL, Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphiles, Bioorg Med Chem Lett 22, 6577-6579 (2012).
    56. Glisoni R, Cuestas ML, Mathet VL, Oubiña JR, Moglioni A, Sosnik A§, Antiviral activity of novel 1-indanone thiosemicarbazones and their inclusion complexes with hydroxypropyl-b-cyclodextrin against the hepatitis C virus (HCV), Eur J Pharm Sci 47, 596-603 (2012).
    57. Ribeiro A, Sosnik A, Chiappetta DA, Veiga F, Concheiro A, Alvarez-Lorenzo C, Single and mixed poloxamine micelles as suitable nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy, J R Soc Interface 9, 2059-2069 (2012).
    58. Sosnik A§, Seremeta KP, Imperiale JC, Chiappetta DA, Novel formulation and drug delivery strategies for the treatment of pediatric poverty related diseases (PRDs), Expert Op Drug Deliv 9, 303-23 (2012).
    59. Glisoni RJ, Chiappetta DA, Moglioni AG, Sosnik A§, Novel 1-indanone thiosemicarbazone antiviral candidates: Aqueous solubilization and physical stabilization by means of cyclodextrins, Pharm Res 29, 739-755 (2012).
    60. Moretton MA, Chiappetta DA, Sosnik A§, Cryoprotection-lyophilisation and physical stabilization of rifampicin-loaded flower-like polymeric micelles, J R Soc Interface 9, 487-502 (2012).
    61. Sosnik A§, Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps with Generally Regarded As Safe (GRAS) nanopharmaceuticals: A review, Adv Drug Deliv Rev 65, 1828-1851 (2013).
    62. Andrade F, das Neves J, Ferreira D, Sosnik A, Sarmento B, Nanotechnology pulmonary delivery to overcome resistance in infectious diseases, Adv Drug Deliv Rev 65, 1816-1827 (2013).
    63. Glisoni RJ, Sosnik A§, Encapsulation of the antimicrobial and immunomodulator drug nitazoxanide within pristine and lactosylated polymeric micelles, J Nanosci Nanotechnol 14, 4670-4682 (2014).
    64. Cuestas ML, Glisoni RJ, Mathet VL, Sosnik A§, Lactosylated poly(ethylene oxide)-poly(propylene oxide) block copolymers for potential active targeting: Synthesis and physicochemical and self-aggregation characterization, J Nanopart Res 15, Art. 1389 (2013).
    65. Glisoni RJ, García-Fernández MJ, Pino M, Gutkind G, Moglioni AG, Alvarez-Lorenzo C, Concheiro A, Sosnik A§, -Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazones, Carbohydr Polym 93, 449-457 (2013).
    66. Moretton MA, Chiappetta DA, Andrade F, das Neves J, Ferreira D, Sarmento B, Sosnik A§, Hydrolyzed galactomannan-modified nanoparticles and flower-like polymeric micelles for the active targeting of rifampicin to macrophages, J Biomed Nanotechnol 9, 1076-1087 (2013).
    67. Minaberry Y, Chiappetta DA, Sosnik A, Jobbagy M, Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties, Biomacromolecules 14, 1-9 (2013).
    68. Garcia Vior C, Marino J, Roguin LP, Sosnik A, Awruch J, Photodynamic effects of zinc(II) phthalocyanine-loaded polymeric micelles in human nasopharynx KB carcinoma cells, Photochem Photobiol 89, 492-500 (2013).
    69. Seremeta KP, Chiappetta DA, Sosnik A§, Poly(e-caprolactone), Eudragit® RS 100 and poly(e-caprolactone)/Eudragit® RS 100 blend submicron particles for the sustained release of the antiretroviral efavirenz, Colloids Surf B: Biointerfaces 102, 441-449 (2013).
    70. Abraham GA, Romero EL, Sosnik A, Nanomedicine in Latin America, J Biomater Tissue Eng 3, 1-3 (2013).
    71. Chiappetta DA, Hocht C, Opezzo JAW, Sosnik A§, Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV, Nanomedicine (Lond.) 8, 223-237 (2013).
    72. Imperiale JC, Sosnik A§, Nanoparticle-in-microparticle delivery systems (NiMDS): Production, routes of administration and clinical potential, J Biomater Tissue Eng 3, 22-38 (2013).
    73. Imperiale JC, Bevilacqua G, Rosa PTV, Sosnik A§, Production of pure indinavir free-base nanoparticles by a Supercritical Anti-Solvent (SAS) method, Drug Dev Ind Pharm, 40,1607-1615 (2014).
    74. Tshweu L, Katata L, Kalombo L, Chiappetta DA, Hocht C, Sosnik A, Swai H, Enhanced oral bioavailability of the antiretroviral efavirenz nano-encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method, Nanomedicine (Lond.) 9, 1821-1833 (2014).
    75. Moretton MA, Hocht C, Taira C, Sosnik A§, Encapsulation of rifampicin within flower-like polymeric micelles enhances the oral bioavailability in a pediatric fixed dose combination with isoniazid, Nanomedicine (Lond.) 9, 1635-1650 (2014).
    76. Seremeta KP, Martínez Pérez S, López Hernández OD, Höcht C, Taira C, Reyes Tur MI, Sosnik A§, Spray-dried didanosine-loaded polymeric particles for enhanced oral bioavailability, Colloids Surf B: Biointerfaces 123, 515-523 (2014).
    77. Sosnik A§, das Neves J, Sarmento B, Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review, Prog Polym Sci 39, 2030-2075 (2014).
    78. Glisoni RJ, Sosnik A§, Novel poly(ethylene oxide)-co-poly(propylene oxide) copolymer-glucose conjugate by the microwave-assisted ring opening of a sugar lactone, Macromol Biosci 14, 1639-1651 (2014).
    79. Sosnik A§, Carcaboso A, Nanomedicines in the future of pediatric therapy, Adv Drug Deliv Rev 73, 140-161 (2014).
    80. Sosnik A§, Alginate particles for oral drug delivery applications: State-of-the-Art, ISRN Pharm 2014, Art. ID 926157 (2014).
    81. Sosnik A§, Production of drug-loaded polymeric nanoparticles by electrospraying technology, J Biomed Nanotechnol 10, 2200-2217 (2014).
    82. Glisoni RJ, Castro EF, Cavallaro LV, Moglioni AG, Sosnik A§, Enhanced activity of 1-indanone thiosemicarbazone/cyclodextrin complexes against a Hepatitis C Virus surrogate model, J Nanosci Nanotechnol 15, 4224-4228 (2015).
    83. Sosnik A§, Seremeta KP, Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers, Adv Colloids Interface Sci 223, 40-54 (2015).
    84. Monterrubio C, Vila-Ubach M, Rodríguez E, Glisoni RJ, Lavarino C, Schaiquevich P, Sosnik A, Mora J, Carcaboso AM, Combined microdialysis-tumor homogenate method for the study of the steady state compartmental distribution of a hydrophobic anticancer drug in patient-derived xenografts, Pharm Res 32, 2889-2900 (2015).
    85. Imperiale JC, Sosnik A§, Cyclodextrin complexation for the improvement of the treatment in infectious diseases, Nanomedicine (Lond.) 10, 1621-1641 (2015).
    86. Jiménez R, Millán D, Suesca E, Sosnik A, Fontanilla MR, Controlled release of an extract of Calendula officinalis flowers from a system based on the incorporation of gelatin-collagen microparticles into collagen I scaffolds: Design and in vitro performance, Drug Deliv Transl Res 5, 209-218 (2015).
    87. Seremeta KP, Höcht C, Taira C, Cortez Tornello PR, Abraham GA, Sosnik A§, Didanosine-loaded poly(epsilon-caprolactone) microparticles by a coaxial electrohydrodynamic atomization (CEHDA) technique, J Mater Chem B 3, 102-111 (2015).
    88. Imperiale JC, Nejamkin P, Del Sole MJ, Lanusse C, Sosnik A§, Novel protease inhibitor Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs, Biomaterials 37, 383-394 (2015).
    89. Calderon M, Sosnik A§, Polymeric soft nanocarriers as smart drug delivery systems: State-of-the-Art and future perspectives, Biotechnol Adv 33, 1277-1278 (2015).
    90. Sosnik A§, Menaker Raskin M, Polymeric micelles in mucosal drug delivery: Challenges towards clinical translation, Biotechnol Adv 33, 1380-1392 (2015).
    91. Glisoni RJ, Quintana S, Molina M, Calderon M, Moglioni AG, Sosnik A§, Chitosan-g-oligo(epsilon-caprolactone) polymeric micelles: Microwave-assisted synthesis and physicochemical and cytocompatibility characterization, J Mater Chem B 3, 4853-4864 (2015).
    92. Roma MI, Hocht C, Chiappetta DA, Di Gennaro SS, Minoia JM, Bramuglia GF, Rubio MC, Sosnik A§, Peroni RN, Tetronic® 904-containing polymeric micelles overcome the overexpression of ABCG2 in the blood-brain barrier of rats and boost the penetration of the antiretroviral efavirenz into the central nervous system, Nanomedicine (Lond.) 10, 2325-2337 (2015).
    93. Sosnik A§, Imperiale JC, Vazquez-Gonzalez B, Munoz-Munoz F, Menaker Raskin M, Burillo G, Cedillo G, Bucio E, Mucoadhesive thermo-responsive chitosan-g-poly(NIPAAm) polymeric micelles via a one-pot gamma radiation-assisted pathway, Colloids Surf B Biointerfaces 136, 900-907 (2015).
    94. Monterrubio C, Pascual-Pasto G, Cano F, Vila-Ubach M, Manzanares A, Schaiquevich P, Tornero JA, Sosnik A, Mora J, Carcaboso AM, SN-38-loaded nanofiber matrices for local control of pediatric solid tumors after subtotal resection surgery, Biomaterials 79, 69-78 (2016).
    95. Menaker Raskin M, Schlachet I, Sosnik A§, Mucoadhesive nanogels by ionotropic crosslinking of chitosan-g-oligo(NiPAam) polymeric micelles as novel drug nanocarriers, Nanomedicine (Lond.) 11, 217-233 (2016).
    96. Rasente RY, Imperiale JC, Lázaro-Martínez JC, Gualco L, Oberkersch R, Sosnik A, G Calabrese, Development and characterization of dermatan sulfate and chitosan polyelectrolyte complexes with potential application in endothelial cell treatment, Carbohydr Polym 144, 362-370 (2016).
    97. Sosnik A§, Drug self-assembly: A phenomenon at the nanometer scale with major impact in the structure-biological properties relationship and the treatment of disease, Prog Mater Sci 82, 39-82 (2016).
    98. das Neves J, Sarmento B, Sosnik A§, Biomedical engineering approaches for HIV/AIDS prophylaxis, diagnostics and therapy, Adv Drug Deliv Rev, 103, 1-4 (2016).
    99. Sosnik A§, Augustine R, Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them, Adv Drug Deliv Rev, 103, 105-120 (2016).
    100. Sridhar K, Rahman H, Sosnik A, Mukherjee U, Natarajan T, Siram K, Krishnamoorthy B, Production of irbesartan nanocrystals by high shear homogenisation and ultra-probe sonication for improved dissolution rate, Curr Drug Deliv, 13, 688-697 (2016).
    101. Martini MF, Glisoni RJ, Sosnik A, Moglioni AG, Pickholz M, Insights on self-aggregation phenomena of 1-indanone thiosemicarbazones and the formation of inclusion complexes with hydroxypropyl-b-cyclodextrin by Molecular Dynamics simulations, J Mol Liq 222, 963-971 (2016).
    102. Schlachet I, Sosnik A§, Protoporphyrin IX-modified chitosan-g-oligo(NiPAam) polymeric micelles: From physical stabilization to permeability characterization in vitro, Biomater Sci 5, 128-140 (2017).
    103. Abu Saleh D, Shimoni O, Sosnik A§, Core-anchored hybrid polymeric micelle-like nanomaterials based on the conjugation of amphiphilic diblocks to the surface of multifunctional nanodiamond anchors, Mater Today Chem 3, 15-26 (2017).
    104. Talal J, Abutbul-Ionita I, Schlachet I, Danino D, Sosnik A§, Amphiphilic Nanoparticle-in-Nanoparticle drug delivery systems exhibiting a surface rate-controlling crosslinked inorganic domains, Chem Mater 29, 873–885 (2017).
    105. Augustine R, Mathew A, Sosnik A§, Metal oxide nanoparticles as versatile therapeutic agents modulating cell signaling pathways: Linking nanotechnology with molecular medicine, Appl Mater Today 7, 91-103 (2017).
    106. Augustine R, Pan D, Sosnik A, Nguyen T, Kalarikkal N, Vincent B, Thomas S, Menu P, Electrospun poly(vinylidene fluoride-trifluoroethylene)/zinc oxide nanocomposite tissue engineering scaffolds with enhanced  cell adhesion and angiogenic properties, Nano Res, in press (2017).
    107. Monterrubio C, Paco S, Olaciregui NG, Pascual-Pasto G, Vila-Ubach M, Cuadrado-Vilanova M, Ferrandiz MM, Glisoni R, Kuplennik N, Cheung N-KV, Mora J, Sosnik A, Carcaboso AM, Targeted drug distribution in tumor extracellular fluid of neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8, J Control Release 255, 108-119 (2017).
    108. Sosnik A§, Seremeta KP, Hydrogels as technology platform for drug delivery applications, Gels, 3, Art. 25 (2017).
    109. Cánepa C, Imperiale J, Berini CA, Lewicki M, Sosnik A, Biglione M, Development of a drug delivery system based on chitosan nanoparticles for oral administration of interferon-alpha, Biomacromolecules, 18, 3302-3309 (2017).
    110. Abu Saleh D, Niskanen J, Xue Y, Golberg D, Winnik FM, Sosnik A§, Boron Nitride Nanotube-Based Amphiphilic Hybrid Nanomaterials for Superior Encapsulation of Hydrophobic Cargos, Mater Today Chem 6, 45-50 (2017).
    111. Moshe H, Davizon Y, Menaker Raskin M, Sosnik A§, Novel Poly(Vinyl Alcohol)-Based Amphiphilic Nanogels by Boric Acid Non-Covalent Crosslinking of Polymeric Micelles, Biomater Sci 5, 2295-2309 (2017).
    112. Cautela M, Moshe H, Sosnik A, Sarmento B, das Neves J, Composite films for vaginal delivery of tenofovir disoproxil fumarate and emtricitabine, Eur J Pham Biopharm, in press (2018).
    113. 113. Bukchin A, Kuplennik N, Carcaboso A, Sosnik A, Effect of Growing Glycosylation Extents on the Self-Assembly and Active Targeting In Vitro of Branched Poly(ethylene oxide)-Poly(Propylene oxide) Block Copolymers, Appl Mater Today 11, 57-69 (2018).
    114. Bukchin A, Pascual-Pasto G, Cuadrado-Vilanova M, Castillo-Ecija H, Monterrubio C, Olaciregui NG, Ordeix L, Mora J, Carcaboso A, Sosnik A§, Glucosylated nanomicelles target glucose-avid pediatric sarcomas, J Control Release, 276, 59-71 (2018).
    115. Augustine R, Levin Ashkenazi D, Sverdlov Arzi R, Zlobin V, Shofti R, Sosnik A§, Nanoparticle-in-Microparticle Oral Drug Delivery System of a Clinically Relevant Darunavir/Ritonavir Antiretroviral Combination, Acta Biomater, in press (2018).
    116. Manzanares A, Restrepo-Perdomo CA, Cano F, Garcia-Alvarez L, Ruiz B, Suñol M, Mora J, Tornero JA, Sosnik A, Carcaboso AM, Tissue biocompatibility of SN-38-loaded anticancer nanofiber matrices, Adv Healthcare Mater, in press (2018).
    117. Noi I, Schlachet I, Kumarasamy M, Sosnik A§, Permeability of chitosan-g-poly(methyl methacrylate) amphiphilic nanoparticles in a model of small intestine in vitro, Polymers, 10, Art. 478 (2018).
    118. Imperiale JC, Acosta G, Sosnik A§, Polymer-based carriers for ophthalmic drug delivery, submitted to J Control Release.
    119. Sverdlov Arzi R, Sosnik A§, Spray drying and electrohydrodynamic atomization techniques for the bottom-up synthesis of pure drug nanocrystals and cocrystals, submitted to Adv Drug Deliv Rev.

§ Corresponding author.


 (B) Book Chapters

  1. Sosnik A, Khan OF, Butler M, Sefton MV, Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications, In: Hydrogels: biological properties and applications, Barbucci R. (Ed.), Springer, pp. 79-96 (2009).
  2. Chiappetta DA, Degrossi J, Lizarazo RA, Salinas DL, Martínez F, Sosnik A§, Molecular implications in the solubilization of the antibacterial agent triclocarban by means of branched poly(ethylene oxide)-poly(propylene oxide) polymeric micelles, In: Polymer Aging, Stabilizers and amphiphilic block copolymers, Segewicz L. and Petrowsky M. (Eds.), Nova Publishers, Hauppauge, NY, Chapter 5, pp. 197-211 (2011).
  3. Alvarez-Lorenzo C, dos Santos FR, Sosnik A, Torres-Labandeira J, Concheiro A, Cyclodextrin-based hydrogels as highly versatile drug delivery systems, In: Handbook of hydrogels: Properties, preparation and applications, Stein DB (Ed.), Nova Publishers, Hauppauge, NY, Chapter 3, pp. 61-102 (2009).
  4. Alvarez-Lorenzo C, Concheiro A, Sosnik A§, Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles and gels in drug delivery: State-of-the-art and future perspectives, In: Handbook of hydrogels: Properties, preparation and applications, Stein DB (Ed.), Nova Publishers, Hauppauge, NY, Chapter 15, pp. 449-484 (2009).
  5. Sosnik A§, Temperature- and pH-sensitive polymeric micelles for drug encapsulation, release and targeting, In: Smart Materials for Drug Delivery, Alvarez-Lorenzo C, Concheiro A (Eds.), Royal Society of Chemistry, London, Chapter 5, pp. 115-147 (2013).
  6. Sosnik A§, Gotelli G, Aplicaciones de la tecnología de radiación de microondas en la síntesis y el procesamiento de biomateriales, In: Biomateriales aplicados al diseño de sistemas terapéuticos avanzados, Sosnik A, Braga M, Sousa H (Eds.), Coimbra University Press, Chapter 7, pp. 255-308 (2015).
  7. Alvarez-Lorenzo, Concheiro A, Sosnik A§, Micelas poliméricas para encapsulación, vectorización y cesión de fármacos, In: Biomateriales aplicados al diseño de sistemas terapéuticos avanzados, Sosnik A, Braga M, Sousa H (Eds.), Coimbra University Press, Chapter 5, pp. 183-217 (2015).
  8. Sosnik A§, Tissue-based in vitro and ex vivo models for nasal permeability studies, In: Concepts and models for drug permeability studies: Cell and tissue-based in vitro culture models, Sarmento B (Ed.), Woodhead Publishing-Elsevier, Chapter 4.3, pp. 237-254 (2015).
  9. Suesca E, Sosnik A, Fontanilla MR, Collagen substrates for soft tissue engineering, In: Frontiers in Biomaterials, Vo. 2, Pillay V, Choonara YE, Kumar P (Eds.), Bentham Science Publishers, Chapter 2, pp. 28-53.
  10. Sosnik A§, Polyester micro and nanosystems for treating HIV, tuberculosis and malaria, In: Handbook ofpolyesterdrug delivery systems, Kumar R (Ed.), Pan Stanford Publishing Ltd., Chapter 17, pp. 563-594 (2016).
  11. Sosnik A§, Nanodrugs in Medicine & Healthcare / Oral Delivery, In: Nanopharmacy – Nanotechnology-based Production of Pharmaceuticals, Cornier J, Kwade A, Owen A, Van de Voorde M (Eds.), Wiley-VCH, Chapter 24, pp. 579-601 (2016).
  12. Sosnik A§, From the “magic bullet” to advanced nanomaterials: An historical perspective, In: Biomedical Applications of Functionalized Nanomaterials, Sarmento B, das Neves J (Eds.), Elsevier, in press.
  13. Seremeta KP, Sosnik A§, Hydrogels in drug delivery, In: Pharmaceutical technology, Manzo R, Nacucchio M (Eds.), University of Buenos Aires Press, accepted.
  14. Sosnik A§, Kumarasamy M, Nanomedicines to overcome efflux transporter-mediated resistance in cancer, In: Drug Efflux Pumps In Cancer Resistance Pathways: From Molecular Recognition To Inhibition Strategies In Chemotherapy, Sosnik A, Bendayan R (Eds.), Elsevier, accepted.

§ Corresponding author.



  1. Cohn D, Sosnik A, Responsive biomedical composites, U.S. #7,425,322.
  2. Cohn D, Sosnik A, Multi-component reverse thermo-sensitive polymeric systems, U.S. #20050008609.
  3. Sosnik A, Chiappetta DA, Hocht C, Aqueous pharmaceutical compositions for the oral administration of antiretroviral agents, National Institute of Industrial Property, Argentina, AR072715.


INVITED Presentations in scientific meetings

(A) Plenary and keynote

  1. “Advances in Nanotechnologies Applied to Therapeutics”. VI Conference of the Pan American Network on Drug Regulatory Harmonization-Pan American Health Organization (PAHO). Brasilia, Brazil 2011. Keynote
  3. “Poly(Vinyl Alcohol)-Based Amphiphilic Nanogels by Non-Covalent Boric Acid Crosslinking”, 34th International Conference of the Polymer Processing Society (PPS-34). Taipei, Taiwan 2018, Keynote
  4. Advanced amphiphilic nanobiomaterials for drug delivery: From design to preclinical evaluation”, 19th International Microscopy Congress (IMC19). Sydney, Australia. To be held in September 2018. Keynote
  5. “Amphiphilic copolymers in advanced drug delivery: From improved mucosal permeability to active targeting”, XVI Latin American Polymer Symposium/XIV Iberamerican Polymers Congress. Mar del Plata, Argentina. To be held in November 2018. Keynote

 (B) Invited

  1. “Polymeric nanocarriers in therapeutics: The potential of polymeric micelles in the encapsulation and the stabilization of drugs”. 2nd School of Pharmaceutical Nanotechnology, Bernal, Argentina 2008.
  2. “HIVS/AIDS: Contributions of the Pharmaceutical Sciences to the treatment of the pediatric patient”. III Congreso Colombiano de Biotecnología/II Seminario Internacional de Bionegocios, Bogota, Colombia 2008.
  3. “In the name of the virus, the Active Pharmaceutical Ingredient and the infected patient: Challenges and potential contributions of Pharmaceutical Technology to the treatment of HIV/AIDS”. BIOOMAT-1st WORKSHOP on BIOMATERIALS, ARTIFICIAL ORGANS AND TISSUE ENGINEERING. Rosario, Argentina 2009.
  4. “The transmutation of the being: From medical devices to novel drug delivery systems”. I Congreso Latinoamericano de Farmacia y Bioquímica Industrial. Buenos Aires, Argentina 2009.
  5. “Infección por el Virus de la Inmunodeficiencia Humana (VIH): Perspectivas para el bordaje multidisciplinario de la farmacoterapia”. NanoMercosur 2009. Buenos Aires, Argentina.
  6. “Small Changes are Big Steps: Making Nanotechnologies Ethically Affordable in Pediatric HIV Pharmacotherapy. First World Conference on Nanomedicine and Drug Delivery”. Kottakam, India 2010.
  7. “Microwave radiation applied to the synthesis of biomaterials”. III Encuentro de Jóvenes Investigadores en Ciencia y Tecnología de Materiales. Concepción del Uruguay, Argentina 2010.
  8. “Nanotecnologías en la optimización de la farmacoterapia del VIH: Estado-del-Arte”. 2º Escuela Latinoamericana de Nanomedicinas. La Plata, Argentina 2010.
  9. “Micelas poliméricas como herramienta nanotecnológica versátil en la optimización de la biodisponibilidad oral de fármacos”. 2º Escuela Latinoamericana de Nanomedicinas. La Plata, Argentina 2010.
  10. “Nuevos-viejos desafíos en el tratamiento de la tuberculosis”. 2º Escuela Latinoamericana de Nanomedicinas. La Plata, Argentina 2010.
  11. “Aplicaciones de biomateriales a la liberación de fármacos en veterinaria. ETIF 2010 Congress and Exposition”. Buenos Aires, Argentina 2010.
  12. “Embracing the spirit of the “Make medicines children size” campaign in HIV/AIDS: How nanotechnologies can make it”. 1st South American Congress of Biopharmacy and Pharmacokinetics/Panamerican Congress of Pharmacy. Porto Alegre, Brazil 2010.
  13. “The pros and contras of innovation: Issues to take advantage of novel technologies in neglected diseases, the HIV case. First Workshop on Nanomedicine for Infectious Diseases of Poverty: Perspectives and Possibilities”. Magaliesberg, South Africa 2011.
  14. “Copolímeros anfifílicos auto-agregables como inhibidores de transportadores de eflujo en la optimización de la farmacoterapia”. Encuentro Anual de la Sociedad Argentina de Farmacología Experimental. Tucumán, Argentina 2011.
  15. “Liberación controlada de antibióticos en el tratamiento de lesiones de piel”. I Argentine Symposium on Medical Devices and Sterilization. Buenos Aires, Argentina 2011.
  16. “Contributions of the nanotechnology to the improvement of Poverty Related Diseases”. XI Encuentro SUPERFICIES Y MATERIALES NANOESTRUCTURADOS 2011. San Martín, Argentina 2011.
  17. “NANOTECHNOLOGY-BASED STRATEGIES FOR DRUG DELIVERY AND TARGETING IN POVERTY-RELATED AND INFECTIOUS DISEASES”. Joint Binational Workshop of the University of Buenos Aires and the University of Freiburg. Freiburg in Breisgau, Germany 2012.
  18. “Nano for HIV”. ICPC Nanonet Project. May 2012 (webinar).
  20. “Nanotechnology-based strategies for the drug delivery and targeting in HIV: Development of an innovative pediatric product of the antiretroviral efavirenz”. II National Nanotechnology Congress. Viña del Mar, Chile 2012.
  21. “Innovación en el desarrollo de productos farmacéuticos en enfermedades desatendidas: El caso VIH”. 3rd Latin American School of Nanomedicine, Potrero de los Funes, Argentina 2012.
  22. “Micelas poliméricas como herramientas para el transporte y el abordaje de la resistencia a fármacos”. 3rd Latin American School of Nanomedicine. Potrero de los Funes, Argentina 2012.
  24. “Polymeric micelles for the enhanced biopharmaceutic performance of the antiretroviral efavirenz”. Regional Meeting of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Buenos Aires, Argentina 2012.
  25. “Perspectives in nanomedicine research in Poverty-related diseases”. II Argentine Symposium of Nanomedicine. Buenos Aires, Argentina 2013.
  26. “Finding the Balance between Innovation and Bench-to-bedside Translation in HIV Therapy”, CLINAM 7/2014-The European Summit for Clinical Nanomedicine and Targeted Medicine, European Foundation for Clinical Nanomedicine. Basel, Switzerland 2014.
  27. “Polymeric micelles for improving the oral bioavailability of drugs: From self-assembly to bench-to-bedside translation”, 2014 IUPAC World Polymer Congress-MACRO 2014. Chiang Mai, Thailand 2014.
  28. “Pediatric nanomedicine: Minimizing the size to maximize the benefit”, Global Research in Pediatrics (GRiP) Network of Excellence “Meet the expert in pediatric formulation”, July 2014 (webinar).
  29. “Do not forget the forgotten diseases…and patients”, Annual Meeting of the Israeli Chapter of the Controlled Release Society. Ma’alot, Israel 2014.
  30. “Nanomedicine for kids: The size matters”, International Course on Tissue Engineering, Regenerative Medicine and New Materials for the Design of Drug Delivery Systems in High Socioeconomic Impact Diseases. Bogota, Colombia 2014.
  31. “Polymeric micelles for oral drug delivery applications”, International Course on Tissue Engineering, Regenerative Medicine and New Materials for the Design of Drug Delivery Systems in High Socioeconomic Impact Diseases. Bogota, Colombia 2014.
  32. “Potential of polymeric micelles as drug carriers for non-parenteral routes”, 29th Umbrella Symposium Technion-RWTH Aachen University-Julich Forschungszentrum. Haifa, Israel 2015.
  33. “The pros and the cons of polymeric micelles as delivery platform by minimally-invasive administration routes: Make it the sticky way”, CLINAM 8/2015-The European Summit for Clinical Nanomedicine and Targeted Medicine, European Foundation for Clinical Nanomedicine. Basel, Switzerland 2015.
  34. “Nano-Drug Delivery Platforms for Improved Therapy of HIV: Only a Scientific Challenge?” Sydney Nanomedicine Conference. Sydney, Australia 2015.
  37. “Innovation in the development of pharmaceutical products for neglected diseases: Some lesson learned from the HIV case”, First Conference on Clinical Nanomedicine. Caracas, Venezuela 2015 (skype conference).
  38. “Novel self-assembly nanocarriers stabilized with mild chemistries”, 81st Meeting of the Israel Chemical Society. Tel Aviv, Israel 2016.
  39. “Polymeric Micelles as a Nano-Drug Delivery System Model: Can We Find a Balance between Sophistication and Clinical Translation?” The First NIMS (Japan) – Technion (Israel) Workshop on “Innovative Materials and Nanotechnology”. Tsukuba, Japan 2016.
  40. “Paediatric Nanomedicine: Challenges to Close the Adult-child Gap Before it Emerges”, CLINAM 9/2016-The European Summit for Clinical Nanomedicine and Targeted Medicine, European Foundation for Clinical Nanomedicine. Basel, Switzerland 2016.
  41. “Non-covalently crosslinked multimicellar systems for more efficient drug delivery applications”, Asian Polymer Association (APA) International Conference on Advanced Polymers, Biomaterials, Bioengineering & Nano Drug Delivery. Flic-En-Flac, Mauritius 2016.
  42. “Innovative strategies for the synthesis of self-assembly amphiphilic nanobiomaterials with advanced features”, Royal Society of Chemistry Biomaterials Interest Annual Conference 2017. Belfast, UK 2017.
  43. “Novel strategies for the design of organic-inorganic amphihilic nanobiomaterials for improved performance in drug delivery”, 45th Annual Meeting of The Israeli Polymer and Plastic Society (IPPS). Ramat Gan, Israel 2017.
  44. “Polymeric micelles stabilized by drug-compatible chemical pathways”, 8th International Congress BioNanoMed 2017. Krems, Austria 2017.
  45. “Advanced self-assembly polymeric nanobiomaterials: From design to engineering”, 9th International Conference on Materials for Advanced Technologies (ICMAT2017). Singapore, Singapore 2017.
  46. “Polymeric micelles as drug delivery platform: Challenges and opportunities”, Controlled Release Society-CoreNet Networking Symposium. Singapore, Singapore 2017.
  47. “Novel polymer-ceramic hybrid amphiphilic nanomaterials with superior properties for drug delivery applications”, Biomaterials International 2017. Fukuoka, Japan 2017.
  48. “Sol-gel in biomedical applications: From pure ceramics to polymer-ceramic hybrids”, 8th School for the Synthesis of Materials: Sol-Gel Processes, Faculty of Exact Sciences, University of Buenos Aires. Buenos Aires, Argentina 2017.
  49. “Pathways for the targeting of nano-drug delivery systems in pediatric disease”, 2nd International Conference on Biomedical Applications of Nanomaterials (ICOBAN2018). Hong Kong, China 2018.
  50. “Carbohydrate pathways to target sugar-avid pediatric tumors with nanomedicines”, 18th Israel Materials Engineering Conference (IMEC18). Dead Sea, Israel 2018.
  51. “Amphiphilic Nanobiomaterials for Advanced Drug Delivery”, 2018 European Materials Research Society Spring Meeting and Exhibit. Strasbourg, France. To be held in June 2018.
  52. “Amphiphilic polymeric nanocarriers to overcome biological barriers”, XXVII INTERNATIONAL MATERIALS RESEARCH CONGRESS. Cancun, Mexico. To be held in August 2018.
  53. “Amphiphilic polymeric nanoparticles to cross biological barriers in drug delivery”, 33° Latin-American Congress of Chemistry (33-CLAQ). Havana, Cuba. To be held in October 2018.



(A) Journals

Drug Nanoparticles and Nano-Cocrystals: From Production and Characterization to Clinical Translation, Advanced Drug Delivery Reviews, under edition. Editors: Sosnik A, Mühlebach S. 

Hydrogels for Drug Delivery, Gels, under edition. Editors: Sosnik A, Seremeta KP. Link

Biomedical engineering approaches for HIV/AIDS prophylaxis, diagnostics and therapy. Advanced Drug Delivery Reviews, under edition. Editors: das Neves J, Sarmento B, Sosnik A. Link

Polymeric soft nanocarriers as smart drug delivery systems: State-of-the-Art and future perspectives. Biotechnology Advances, under edition. Editors: M Calderon, A Sosnik.

Nanobiotechnology. BioMed Research International (2013). Editors: CJ Valguga, H Mu, A Sosnik, SN Diniz. Link

Nanomedicines in Latin America. Journal of Biomaterials and Tissue Engineering, 3, Pages 1-172 (2013). Editors: GA Abraham, E Romero, A Sosnik. Link

Chitosan and chitosan derivatives for biological applications: Chemistry and functionalization. International Journal of Carbohydrate Chemistry (2011). Editors: B Sarmento, F Goycoolea, A Sosnik, J das Neves. Link

Nanotechnology solutions for infectious diseases in developing nations. Advanced Drug Delivery Reviews 62, 375-590 (2010). Editors: A Sosnik, M Amiji. Link


(B) Books

Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition to Inhibition Strategies in Chemotherapy. Elsevier (under edition). Editors: Sosnik A, Bendayan R.

Biomateriales aplicados al diseño de sistemas terapéuticos avanzados. Coimbra University Press. Editors: H Sousa, M Braga, A Sosnik. Link